Human evolution: How recent were the Y chromosome ancestors?

نویسنده

  • J.F.Y Brookfield
چکیده

Recent findings of low sequence variability of Y chromosome genes has led to suggestions that the most recent ancestor of human Y chromosomes existed around 50,000 years ago and human population size expanded about 28,000 years ago. But what level of confidence can we have in these estimates?

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

I-3: Human Y Chromosome Proteome Project 2012 Update

The Human Genome Project has generated a blueprint for the approximately 20,300 gene-encoded proteins potentially active in any of 230 cell types that make up the human body (human proteome). However, based on the UniProtKB/Swiss-Prot database content, about 6000 of at the protein level; for many others, there is very little information related to protein function, abundance, subcellular locali...

متن کامل

Somewhat Less-Recent Common Ancestors of All Present-Day Individuals

The notion of our common ancestors has received considerable attention of late in both the scientific and lay communities. Principally this attention has focused on ‘Mitochondrial Eve,’ defined to be the woman who lies at the confluence of our maternal ancestry lines, and who is believed to have lived 100,000–200,000 years ago. More recent attention has been given to our common paternal ancesto...

متن کامل

A populationwide coalescent analysis of Icelandic matrilineal and patrilineal genealogies: evidence for a faster evolutionary rate of mtDNA lineages than Y chromosomes.

Historical inferences from genetic data increasingly depend on assumptions about the genealogical process that shapes the frequencies of alleles over time. Yet little is known about the structure of human genealogies over long periods of time and how they depart from expectations of standard demographic models, such as that attributed to Wright and Fisher. To obtain such information and to exam...

متن کامل

Deep divergences of human gene trees and models of human origins.

Two competing hypotheses are at the forefront of the debate on modern human origins. In the first scenario, known as the recent Out-of-Africa hypothesis, modern humans arose in Africa about 100,000-200,000 years ago and spread throughout the world by replacing the local archaic human populations. By contrast, the second hypothesis posits substantial gene flow between archaic and emerging modern...

متن کامل

I-39: Exploring New Frontiers in Human Y Chromosome Proteome Project

The major goal of the Chromosome-Centric Human Proteome Project (C-HPP) is to systematically map the entire human proteome with the intent to enhance our understanding of human biology at the cellular level. However, this goal may be hindered by the lack of quality observations of given proteins due to absence of expression in a given tissue, very low abundance, and expression only in rare samp...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current Biology

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2000